Discover the Dark Side of New Orleans with the Pestilence, Pandemic, and Plague Tour

If you’re looking for a different way to experience New Orleans, this Pestilence, Pandemic, and Plague Tour offers a fascinating and slightly eerie look at the city’s past. For just $37 per person, you get about two hours of storytelling that takes you through some of the city’s most historic sites, revealing stories of yellow fever, cholera, and other epidemics that shaped the city’s culture. Your guide—often praised for their knowledge and humor—will lead you through the French Quarter, Jackson Square, and the New Orleans Pharmacy Museum, offering insights that typical city tours rarely touch.
What we love most is how this tour intertwines medical history with the region’s voodoo and religious traditions, creating a multi-layered narrative that makes the past come alive. Another highlight is the small group size (up to 56 participants), ensuring you’re not just another face in the crowd but part of an engaging conversation. The expert guides—like Mikko, Dalvin, and Dane—are often singled out for their enthusiasm and depth of knowledge, making the experience both educational and entertaining.
One possible hitch? Since the tour is outdoor and involves walking, wearing comfortable shoes and being prepared for the daytime weather in spring or summer is wise. Also, as the tour covers some sensitive historical content, those with an interest in health crises or dark history will find it especially rewarding. This experience suits travelers who love history, enjoy stories with a twist of the macabre, or simply want a deeper understanding of what’s behind New Orleans’ reputation for mystery and resilience.
Key Points
- Unique Perspective: Focuses on New Orleans’ history with disease outbreaks and their impact on the city’s culture.
- Expert Guides: Guides like Mikko and Dalvin receive high praise for their knowledge, humor, and engaging storytelling.
- Authentic Experience: Visits key sites like the French Quarter, Jackson Square, and the Pharmacy Museum, with stories often overlooked by typical tours.
- Value for Money: At $37, the tour offers a well-paced, informative experience that covers a lot of ground in just two hours.
- Group Size & Comfort: Small groups maximize interaction; comfortable shoes and weather gear are recommended.
- Historical & Cultural Blend: Combines medical, religious, and cultural stories—perfect for those with curiosity about how disease influenced New Orleans.
Planning more time in New Orleans? We've covered other experiences worth considering.
A Closer Look at the Tour Itinerary

Starting Point: New Orleans Pharmacy Museum
We begin our journey at the New Orleans Pharmacy Museum, where the focus is on the fascinating and sometimes bizarre history of medicine during pandemics. The museum, which you can choose to explore further on your own afterward, offers a glimpse into how medicine was approached in times of crisis—sometimes through strange remedies and practices. Our guide provides context and highlights stories that reveal how medical responses evolved over centuries.
Although admission isn’t included, many find visiting the museum before or after the tour adds to the understanding of how health crises shaped local practices. It’s a curious start that sets the tone for the darker tales ahead.
Jackson Square: The Heart of the French Quarter
Next, we move to Jackson Square, a lively hub surrounded by historic buildings and street performers. Here, the guide discusses how diseases like yellow fever swept through the city, often striking during Mardi Gras or other celebrations, disrupting the city’s rhythm. The stories shared here are often overlooked but are essential for understanding New Orleans’ resilience in the face of repeated health crises.
The French Quarter Walk: An Intimate Exploration
The heart of the tour involves a 1-hour and 20-minute walk through the French Quarter, exploring streets and landmarks linked to historic and recent pandemics. As we stroll, stories of quarantine, voodoo rituals for protection, and public health measures come to life. Many reviewers comment on the enriching details and the guides’ ability to weave folklore, history, and science seamlessly.
One reviewer noted, “Our tour guide, Dalvin, provided an entertaining and insightful tour. His knowledge and love for New Orleans came through during the tour as he was able to point out interesting and obscure details all along the way.”
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Final Stop: The French Quarter & Nearby Streets
Additional stops include various locations significant to the city’s encounters with disease. The guide shares stories that you’d likely miss on your own—like how certain architectural features or local customs were influenced by the need to cope with outbreaks. The stories often highlight the balance between voodoo, religion, and medicine, giving you a broader picture of how the city’s culture adapted through dark times.
What Makes This Tour Stand Out?

Knowledgeable Guides with a Sense of Humor
Reviewers consistently praise guides like Mikko, Dane, and Dalvin for their deep knowledge and their ability to make complex topics engaging. Their humor and storytelling style keep the atmosphere lively, even when discussing grim parts of history. One reviewer noted, “Mikko showed me a trash can—his wit made the tour memorable!”
Authentic & Overlooked Stories
Instead of just hitting the usual tourist spots, the tour digs into lesser-known stories—like the medical practices during plagues or the voodoo charms used for protection. This approach offers a more nuanced understanding of how disease shaped local customs, which adds depth to your visit.
Good Value & Well-Paced
At $37 for approximately two hours, the tour is considered good value—especially considering the expert guidance and the unique content. Reviewers mention that the tour’s pacing is just right—informative without feeling rushed, and often customized to the group’s interests.
Accessibility & Group Size
The tour boasts a maximum of 56 travelers, making it easier to ask questions and hear the guide. Many reviews mention that tour guides are mindful of weather conditions and group comfort, advising you to wear comfortable shoes and bring water—especially in warmer months.
The Benefits for Travelers

This tour is perfect for those who love medical history, culture, or dark tales. It offers an educational yet entertaining experience that adds layers to your understanding of New Orleans’ quirky, resilient character. It’s also ideal for people interested in voodoo, religion, and the city’s response to crises—all woven into the stories the guides tell.
If you’re a history buff or a curious traveler eager to explore how pandemics shaped the city, you’ll find this tour both enriching and surprisingly fun. Plus, with the small group setting and knowledgeable guides, you’ll get a more personal, memorable experience.
Final Thoughts

In essence, the New Orleans Pestilence, Pandemic, and Plague Tour offers a rare peek into the city’s hidden stories of disease and resilience. It’s a well-priced option that appeals to those interested in more than just the surface attractions—a chance to understand the unseen forces that helped shape New Orleans’ unique culture. The expert guides, engaging storytelling, and focus on lesser-known history make it stand out among the city’s many walking tours.
This experience suits travelers who enjoy history with a twist, appreciate local folklore, or want to deepen their understanding of how public health and culture intersected over centuries. If you’re ready to explore the city’s darker past while learning about its lighter resilience, this tour is a clever, compelling choice.
FAQ

How long is the tour?
The tour lasts approximately 2 hours, covering key sites in the French Quarter and nearby areas.
Where does the tour start?
It begins at 815 Toulouse Street, New Orleans, and ends near Bourbon Street and Dumaine Street.
What is the price?
The tour costs $37 per person, offering good value considering the depth of stories and guided experience.
Is admission to the museums included?
No, the New Orleans Pharmacy Museum admission is not included, but you can visit after the tour if you wish.
Are the guides knowledgeable?
Yes, reviews consistently praise guides like Mikko and Dalvin for their expertise, humor, and engaging storytelling.
Is the tour suitable for all ages?
While it’s generally accessible with moderate walking, the dark historical content might be more suited for adults or older children interested in history and culture.
Can I cancel if my plans change?
Yes, you can cancel up to 24 hours in advance for a full refund. Cancellations within 24 hours are not refunded.
Is there a group size limit?
Yes, the tour accommodates up to 56 travelers, ensuring a more personal experience and easier communication with guides.
If exploring New Orleans’ darker history sounds intriguing, this tour offers a compelling mix of history, culture, and storytelling that will leave you with a new appreciation for the city’s resilience in the face of disease.
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